NCT01475175

Adaptive Cardiac Resynchronization Therapy Optimization at Rest and During Exercise (AdOPT CRT)

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Medtronic Cardiac Rhythm and Heart Failure · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The AdOPT Cardiac Resynchronization Therapy (CRT) study is an acute, prospective, multi-center, non-randomized investigational study designed to compare indices of cardiac function at device settings optimized using the investigational Adaptive CRT (aCRT) algorithm versus nominal programming. The comparison will be performed during rest, atrial pacing and sub-maximal exercise. AdOPT CRT is a sub study of the Adaptive CRT Study (NTC00980057) being conducted in Europe.

Detailed description

Adaptive CRT is an implantable heart failure device feature that attempts to optimize CRT without echocardiographic testing.

Conditions

• Heart Failure

Interventions

Type	Name	Description
DEVICE	CRT pacing at rest and during exercise	CRT pacing with aCRT settings and BiV pacing with nominal programming at rest and during submaximal exercise

Timeline

• Start date: 2011-11-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2011-11-21
• Last updated: 2019-08-05
• Results posted: 2012-10-12

Locations

7 sites across 6 countries: Austria, Belgium, Denmark, Germany, Netherlands, Norway