NCT01473849

Impact of Cytomegalovirus (CMV) Replication Over Hepatitis C Recurrence in Liver Transplant Recipients

Non-interventional, Prospective Study to Evaluate the Impact of CMV Replication Over Hepatitis C Recurrence in Liver Transplant Recipients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 179 (estimated)
• Sponsor: Sociedad Española de Trasplante Hepático · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The relationship between cytomegalovirus infection and recurrence of hepatitis C in liver transplant recipients remains controversial. Although some studies (Teixeira et al., 2000; Singh et al., 2005)have not found an association between recurrence of hepatitis C and CMV infection, studies such as Rosen et al. show that 50% of patients with CMV infection suffered cirrhosis durig follow-up period, while between not-infected patients the rate was 11%. To clarify this question, a non-interventional study will be carried out in order to assess if CMV replication is a risk factor for graft dysfunction in liver transplant recipients.

Conditions

• Cytomegalovirus Infection
• Hepatitis C

Timeline

• Start date: 2010-05-01
• Primary completion: 2013-03-01
• Completion: 2013-04-01
• First posted: 2011-11-17
• Last updated: 2012-12-20

Locations

13 sites across 1 country: Spain