NCT01473173

Safety, Tolerability, PK, PD of Escalating Single and Multiple Oral Doses of CJ-12420 in Healthy Male Subjects

A Phase I, Randomized, Double-Blind, Placebo-Controlled, Dose Escalation Study, to Investigate the Safety, Tolerability, PK and PD of Escalating Single and Multiple Oral Doses of CJ-12420 in Healthy Male Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 59 (actual)
• Sponsor: HK inno.N Corporation · Industry
• Sex: Male
• Age: 20 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The objectives of this study are: * To evaluate the safety and tolerability of single and multiple oral doses of CJ-12420 in healthy male subjects. * To evaluate the single- and multiple-dose PK of orally administered CJ-12420 in healthy male subjects. * To evaluate the single- and multiple-dose PD of orally administered CJ-12420 in healthy male subjects. * To compare the multiple-dose pharmacodynamics (PD) of orally administered CJ-12420 and esomeprazole in healthy male subjects.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	CJ-12420
DRUG	Esomeprazole 40mg

Timeline

• Start date: 2011-11-01
• Primary completion: 2012-08-01
• Completion: 2012-08-01
• First posted: 2011-11-17
• Last updated: 2013-04-10

Locations

1 site across 1 country: South Korea