Clinical Trials Directory

Trials / Unknown

UnknownNCT01471288

Effect of Carum Carvi on Thyroid Hormones and TSH Level

Evaluation of the Effect of Carum Carvi on Levels of Plasma Thyroid Hormones and TSH Level in Patients on Thyroid Hormone Therapy and Normal Controls.

Status
Unknown
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
40 (estimated)
Sponsor
Mashhad University of Medical Sciences · Academic / Other
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

Carum Carvi has been frequently used in traditional medicine for a variety of disease ranging from dyspepsia to Alzheimer's disease.We observed high TSH levels in few patients with thyroid cancer who receiving Carum Carvi despite being on suppressive dose of levothyroxin. TSH level returned to normal after discontinuation of the Carum carvi. This observation led to a pilot study for evaluation of the effect of carum carvi on thyroid function.

Conditions

Interventions

TypeNameDescription
DRUGCarum Cravi40mg/kg of body weight
DRUGPlaceboPlacebo

Timeline

Start date
2011-05-01
Primary completion
2011-12-01
First posted
2011-11-15
Last updated
2011-11-15

Locations

1 site across 1 country: Iran

Source: ClinicalTrials.gov record NCT01471288. Inclusion in this directory is not an endorsement.