NCT01466465

Vitamin D and Grass Pollen Specific Immunotherapy

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

Allergen-specific immunotherapy is the only causal therapy of Immunoglobulin E-induced allergies like allergic rhinoconjunctivitis. Despite progress during the last decades it is limited by a long treatment time and high non-responder frequency. Based on experimental and epidemiological evidences we hypothesize that vitamin D can act as an effective immunomodulatory adjuvant to overcome these limitations.

Conditions

• Allergic Rhinoconjunctivitis

Interventions

Type	Name	Description
DRUG	Cholecalciferol	given orally, once daily, before grass pollen season
OTHER	middle-chain fatty acids (carrier)	given orally, once daily, before grass pollen season

Timeline

• Start date: 2011-10-01
• Primary completion: 2015-01-01
• Completion: 2015-01-01
• First posted: 2011-11-08
• Last updated: 2015-06-25

Locations

1 site across 1 country: Germany