Trials / Completed
CompletedNCT01465646
Bioavailability Investigations of Thyronajod Mite Tablets of Dosage Strengths 50 μg Levothyrox-ine/75 μg Iodine, and 100 μg Levothyroxine/75 μg Iodine vs. a Levothyroxine Drinking-Solution: A Randomised Cross Over Study in Healthy Male Individuals. Currently: 100 μg/ 75 μg Tablets
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Heidelberg University · Academic / Other
- Sex
- Male
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to measure the area under the curve (AUC0-48h; extent of systemic availability) and the maxi-mum concentrations (Cmax) of total serum levothyroxine (TT4, bound and free fraction) after a single pharmacological dose of 600 μg administered as tablets also containing iodine supple-ments vs. the same dose of levothyroxine administered as a reference solution without iodine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | levothyroxine | |
| DRUG | levothyroxine |
Timeline
- Start date
- 2003-06-01
- Primary completion
- 2003-12-01
- Completion
- 2003-12-01
- First posted
- 2011-11-07
- Last updated
- 2011-11-07
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT01465646. Inclusion in this directory is not an endorsement.