NCT01465373

Vaginal Progesterone Versus Progesterone in Oil in Donor Egg Recipient In Vitro Fertilization Cycles Utilizing Vitrified Donor Eggs

Comparison of the Effectiveness of Micronized Vaginal Progesterone (Endometrin, Ferring) Vs. Progesterone in Oil for Luteal Phase Support in Donor Egg Recipient IVF Cycles Utilizing Previously Vitrified Donor Oocytes

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Fertility Centers of Illinois · Academic / Other
• Sex: Female
• Age: 21 Years – 49 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to evaluate both pharmaceutical therapy and advanced treatment techniques for infertile patients requiring in-vitro fertilization utilizing donor eggs.

Detailed description

The primary objective of this study is to evaluate the clinical pregnancy rate of micronized progesterone (Endometrin, Ferring Pharmaceuticals) compared to progesterone in oil injections in in-vitro fertilization (IVF) donor egg recipients. The secondary objective is to evaluate the effectiveness of freezing/vitrification of donor eggs. Effectiveness of vitrification will be evaluated by egg thaw/survival, fertilization, and implantation rates.

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	Endometrin	100 mg per vagina TID
DRUG	Progesterone in Oil	50 mg IM injection daily

Timeline

• Start date: 2010-02-01
• Primary completion: 2011-09-01
• Completion: 2011-09-01
• First posted: 2011-11-04
• Last updated: 2011-11-04

Locations

1 site across 1 country: United States