Trials / Completed
CompletedNCT01464567
Spontaneous Breathing Trials Using Pressure-Support or T-Tube in Chronic Obstructive Pulmonary Disease Patients Weaning Mechanical Ventilation
Comparison Between Spontaneous Breathing Trials Through Pressure-Support Ventilation or "T" Tube in the Weaning of Mechanical Ventilation in Patients With Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 190 (actual)
- Sponsor
- Hospital Nossa Senhora da Conceicao · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Weaning of mechanical ventilation (MV) is an essential part in management of patients with Chronic Obstructive Pulmonary Disease (COPD) when critically ill. The best strategy to be used has not been established. Objective: To compare the Spontaneous Breathing Trial (SBT) in Pressure Support Ventilation with SBT through "T" tube in weaning of MV in patients with COPD. Design: Randomized Clinical Trial. Methods: This study will include patients with COPD, admitted to the Intensive Care Unit of Hospital Nossa Senhora da Conceição, undergoing MV for at least 48 hours. When considered by the care team ready for SBT, they will be randomized to one of the following strategies: SBT in Pressure Support or SBT through "T" Tube. The primary endpoint of this study will be the reduction in the days spent on MV. Other outcomes measured will be mortality, extubation and success rate, time to weaning of MV, length of ICU stay and incidence of tracheostomy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | "T" Tube Spontaneous Breathing Trial | "T" Tube ventilation for 30 minutes |
| PROCEDURE | Pressure Support Ventilation | Pressure-Support Ventilation for 30 minutes |
Timeline
- Start date
- 2012-01-01
- Primary completion
- 2016-05-01
- Completion
- 2016-05-01
- First posted
- 2011-11-03
- Last updated
- 2016-11-25
Locations
2 sites across 1 country: Brazil
Source: ClinicalTrials.gov record NCT01464567. Inclusion in this directory is not an endorsement.