Trials / Completed
CompletedNCT01459900
Renal Sympathectomy in Treatment Resistant Essential Hypertension, a Sham Controlled Randomized Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 69 (actual)
- Sponsor
- Aarhus University Hospital Skejby · Academic / Other
- Sex
- All
- Age
- 30 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this double blind, randomized and sham controlled study is to determine whether renal denervation in terms of catheter based ablation in the renal arteries is effective in lowering blood pressure in patients with treatment resistant hypertension. The blood pressure lowering effect will be evaluated by 24 hours ambulatory blood pressure measurement at baseline and after 1, 3 and 6 months of follow up. Secondary end point evaluation concerns hemodynamic measures using echocardiography, applanation tonometry and forearm plethysmography.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Renal artery ablation | Catheter based renal denervation by applying low power radiofrequency to the renal artery using the Ardian Medtronic Simplicity Catheter, introduced by femoral artery access. |
| PROCEDURE | Renal angiography | Renal angiography by femoral access. |
Timeline
- Start date
- 2011-09-01
- Primary completion
- 2015-02-01
- Completion
- 2015-02-01
- First posted
- 2011-10-26
- Last updated
- 2016-09-20
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT01459900. Inclusion in this directory is not an endorsement.