NCT01458262

Observational Study on the Clinical Impact of Desaturation During Liver Surgery

Observational Study on the Clinical Impact of Systemic and Cerebral Desaturation During Liver Transplantation and Hepatectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the clinical impact of cerebral and systemic desaturation during liver transplantation and resection on post-operative complications.

Detailed description

This is an observational study. Cerebral and systemic oxymetry (rSO2) using near infrared spectroscopy (NIRS, Invos 5100; Somanet- ics Corporation, Troy, MI) will be performed on all patients with 4 optodes (right and left temporal area, arm and leg). Continuous rSO2 values will be stored on a hard disk with a 15 seconds update within intraoperative period and first 4 hours after the surgery. Desaturation phases (saturation decrease more than 20% of the basal value for more than 15 seconds) will be correlated to operative procedure or events. Postoperative adverse events will be collected. A correlation between desaturation and postoperative adverse events will be done with a multiple linear regression model.

Conditions

• Cerebral Desaturation

Interventions

Type	Name	Description
OTHER	systemic and cerebral oxymetry	oxymetry measurement using near infrared spectroscopy

Timeline

• Start date: 2011-09-01
• Primary completion: 2013-10-01
• Completion: 2014-01-01
• First posted: 2011-10-24
• Last updated: 2014-01-29

Locations

1 site across 1 country: Canada