NCT01456299

Laryngeal Mask Airway (LMA) Insertion With Sevoflurane and Remifentanil

Target-controlled Infusion of Remifentanil for Laryngeal Mask Airway Insertion During Sevoflurane Induction in Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 102 (actual)
• Sponsor: Gachon University Gil Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to determine the most suitable effect-site concentration of remifentanil for the LMA insertion during inhaled induction with 8% sevoflurane in adults.

Detailed description

For practical purposes, opioids with the ability to suppress upper airway reflexes have been used to facilitate insertion of the LMA during anaesthesia induction. To date, however, there have been no published reports addressing the use of remifentanil to facilitate LMA insertion during sevoflurane inhalation induction in adults. Therefore, the purpose of this study was to determine the most suitable effect-site concentration of remifentanil target-controlled infusion (TCI) for the LMA insertion during inhaled induction with 8% sevoflurane in adults.

Conditions

• Laryngismus

Interventions

Type	Name	Description
DRUG	Remifentanil 1	"Remifentanil 1": "The R1 group, which received a target effect-site remifentanil concentration of 1 ng/ml.
DRUG	Control	The control group, which received an infusion of normal saline
DRUG	Remifentanil 2	"Remifentanil 2": "The R2group, which received a target effect-site remifentanil concentration of 2 ng/ml.

Timeline

• Start date: 2011-04-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2011-10-20
• Last updated: 2019-03-15
• Results posted: 2014-04-04

Locations

1 site across 1 country: South Korea