NCT01456156

Study of Postoperative 3D-CRT/IMRT in Hepatocellular Carcinoma

Phase 2 Study of Postoperative Three-dimensional Conformal Radiation Therapy/Intensive Modulated Radiation Therapy in Hepatocellular Carcinoma: a Single Center Prospective Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Chinese Academy of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Hepatectomy is difficult when the tumor is adjacent to the big vessels of the liver and some patients can not receive radical resection. Such patients have high risk of recurrence. Tumor resection and postoperative radiation is an option for such patients to achieve radical treatment and radiation may reduce local recurrence.

Detailed description

Patients with risk factors of recurrence receive postoperative radiotherapy using intensive modulated radiation therapy (IMRT) or three-dimensional conformal radiation therapy (3DCRT). The clinical target volume includes tumor bed. The dose will be 50-60Gy/25-30f. Overall survival, local-recurrence free survival, disease free survival and toxicity need be observed.

Conditions

• Hepatocellular Cancer

Interventions

Type	Name	Description
RADIATION	postoperative radiotherapy	IMRT or 3DCRT, 50-60Gy to the tumor bed

Timeline

• Start date: 2008-01-01
• Primary completion: 2017-01-01
• Completion: 2017-01-01
• First posted: 2011-10-20
• Last updated: 2017-07-05

Locations

1 site across 1 country: China