NCT01452841

A Grapefruit Feeding Trial in Healthy, Overweight Adults

Efficiency of Daily Grapefruit Exposure in Reducing Body Weight and Inflammatory Markers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 85 (actual)
• Sponsor: University of Arizona · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Folklore has suggested that consuming grapefruit may promote weight control. Sparse data exist to support this hypothesis, though there is some evidence of health promotional effects regarding blood pressure and lipid profiles. The aims of this randomized controlled trial are to determine the role of grapefruit in: 1. Reducing weight 2. Reducing blood pressure 3. Reducing inflammation 4. Improving the lipid profile. The investigators hypothesize that six weeks of daily consumption of grapefruit will reduce weight, blood pressure, and inflammation while improving the lipid profile in overweight, healthy adults.

Conditions

• Weight Loss
• Obesity
• Cardiovascular Risk Factors

Interventions

Type	Name	Description
OTHER	Grapefruit	1.5 Rio Red Grapefruit consumed daily for 6 weeks
OTHER	Control	Participants followed a diet low in bioactive rich fruits and vegetables and avoided citrus for six weeks

Timeline

• Start date: 2009-08-01
• Primary completion: 2011-04-01
• Completion: 2011-04-01
• First posted: 2011-10-17
• Last updated: 2011-10-17

Locations

1 site across 1 country: United States