NCT01452425

In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome

In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome.

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Université Catholique de Louvain · Academic / Other
• Sex: Male
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular compartment pressures, and is a rare but serious postoperative complication. The INVOS (In Vivo Optical Spectroscopy) monitors tissular oxygenation continuously and non-invasively. The objective is to develop a model mimicking the physiopathology of MCS to assess the interest of the INVOS in this case.

Detailed description

After inflation of a tourniquet (pressure equal to the mean arterial pressure, we will obtain a model of slight venous congestion and arterial hypoperfusion. A comparison will be made between INVOS monitoring, sensory deficits, pain, electromyography and invasive pressure.

Conditions

• Human Volunteers

Interventions

Type	Name	Description
DEVICE	Tourniquet	Inflation of a tourniquet (pressure equal to the mean arterial pressure) obtaining a model of slight venous congestion and arterial hypoperfusion
DEVICE	INVOS assessment	Near Infraread spectroscopy, non invasive
DEVICE	EMG assessment	Electromyography, non invasive

Timeline

• Start date: 2011-10-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2011-10-14
• Last updated: 2014-12-22
• Results posted: 2014-12-22

Locations

1 site across 1 country: Belgium