Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT01452334

Safety Study of Anti-Programmed Death-Ligand 1 in Hematologic Malignancy

A Phase I Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Immunoregulatory Activity, and Preliminary Antitumor Activity of Anti-Programmed-Death-Ligand 1 (PD-L1) Antibody (BMS-936559) in Subjects With Relapsed or Refractory Hematologic Malignancy

Status
Withdrawn
Phase
Phase 1
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the side effects of treatment with the monoclonal antibody anti-PD-L1 (BMS-936559) in subjects with compromised bone marrow function and the dose that should be recommended for use in future studies.

Conditions

Interventions

TypeNameDescription
BIOLOGICALBMS-936559 (Anti PD-L1)Injection for infusion, Intravenous (IV), 1, 3 or 10 mg/kg, Every 2 weeks, 48-96 weeks depending on response

Timeline

Start date
2011-11-01
Primary completion
2014-11-01
Completion
2014-11-01
First posted
2011-10-14
Last updated
2012-02-23

Source: ClinicalTrials.gov record NCT01452334. Inclusion in this directory is not an endorsement.