Trials / Unknown
UnknownNCT01450956
The Protective Effects of Sevoflurane in Pediatric Cardiac Surgery
The Protective Effects of Sevoflurane Application During CPB on Pediatric Patients Underwent Cardiac Surgery: a Randomized, Controlled, Blinded Clinical Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- Sponsor
- Xijing Hospital · Academic / Other
- Sex
- All
- Age
- 1 Month – 24 Months
- Healthy volunteers
- Not accepted
Summary
During repair of a congenital heart defect the child is exposed to myocardial hypoxia. Recent studies have suggested that the paediatric myocardium is more sensitive to hypoxia and cardioplegic arrest than the adult. The protective effect of halogenated agents on ischaemia and reperfusion injury has been investigated widely in adults. The investigators hypothesis that sevoflurane applied during cardiopulmonary bypass might afford better myocardial protection during paediatric cardiac surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sevoflurane | Sevoflurane will be given at a concentration of 2% through oxygenator during CPB |
| OTHER | Control | Patients will receive only oxygen and air through oxygenator |
Timeline
- Start date
- 2011-09-01
- Primary completion
- 2012-01-01
- Completion
- 2012-01-01
- First posted
- 2011-10-13
- Last updated
- 2011-11-28
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT01450956. Inclusion in this directory is not an endorsement.