NCT01447095

Effects of Prostacyclin Infusion on Cerebral Vessels and Metabolism in Patients With Subarachnoid Haemorrhage

Effect of Prostacyclin Infusion on Cerebral Vessels, Cerebral Bloodflow and Cerebral Metabolism in Patients With Subarachnoid Haemorrhage

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Rune Rasmussen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether prostacyclin is effective in prevention of cerebral vasospasm in patients with subarachnoidal hemorrhage (SAH).

Conditions

• Subarachnoid Hemorrhage

Interventions

Type	Name	Description
DRUG	Prostacyclin 1 ng/kg/min	Continuous i.v. infusion of epoprostenol 1 ng/kg/min day 5-10 after SAH
DRUG	Prostacyclin 2 ng/kg/min	Continuous i.v. infusion of epoprostenol 2 ng/kg/min day 5-10 after SAH
DRUG	Placebo	Continuous i.v. infusion with placebo day 5-10 after SAH

Timeline

• Start date: 2011-10-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2011-10-05
• Last updated: 2014-07-21

Locations

1 site across 1 country: Denmark