NCT01444508

Effect of Colloid Versus Crystalloid on Coagulation

Effect of Colloid Versus Crystalloid on Coagulation in Elective Urological Surgery

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: K. C. Rasmussen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In order to reduce bloodloss and need for transfusion to investigate the effect of colloid and crystalloid on coagulation assuming no difference between the groups.

Conditions

• Bloodloss

Interventions

Type	Name	Description
DRUG	Ringer-lactate "SAD"	Lactated Ringer's is administrated intravenously in the dosis of max. 35 ml/kg during the operation after securing normovolaemia with Nexfin Monitor at induction of the anaesthesia: if bolus infusion of 200 ml increases stroke volume more than 10 % the patient is not assumed normovolaemic and bolus infusions are repeated until normovolaemic status is achieved.
DRUG	HES 130/04	Voluven is administered intravenously in the doses of max. 35 ml/kg during the operation. Normovolaemia is achieved in the same way as described in intervention by Ringer-lactate "SAD".

Timeline

• Start date: 2011-09-01
• Primary completion: 2013-04-01
• Completion: 2013-12-01
• First posted: 2011-09-30
• Last updated: 2013-12-13

Locations

1 site across 1 country: Denmark