NCT01443962

The Effect of Positive End Expiratory Pressure (PEEP) During Laparoscopic Cholecystectomy

The Effect of PEEP on Regional Cerebral Oxygen Saturation During Laparoscopic Cholecystectomy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Gachon University Gil Medical Center · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

During the laparoscopic cholecystectomy, Pneumoperitoneum could affect to the regional oxygen saturation of brain. positive end expiratory pressure (PEEP)could improve the respiratory parameters include oxygenation. So applying PEEP could improve the regional brain oxygen saturation (rSO2)

Detailed description

During the laparoscopic cholecystectomy, Pneumoperitoneum could affect to the regional oxygen saturation of brain due to increased intracranial pressure, central venous pressure and make worse to respiratory parameters. Positive end expiratory pressure could improve the respiratory parameters include oxygenation. So applying PEEP could improve the regional oxygen saturation of brain during the pneumoperitoneum during the laparoscopic cholecystectomy.

Conditions

• Brain Ischemia

Interventions

Type	Name	Description
OTHER	PEEP	applying PEEP 0 cmH2O during pneumoperitoneum continuously
OTHER	ZEEP	applying PEEP 10 cmH2O during pneumoperitoneum continuously

Timeline

• Start date: 2011-11-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2011-09-30
• Last updated: 2013-02-05

Locations

1 site across 1 country: South Korea