NCT01443013

Analysis of Foxp3 and Vimentin Expression in Renal Transplant Recipient

Predictive Value Analysis of Messenger Ribonucleic Acid (mRNA) Urinary Expression of Foxp3 and Vimentin on Graft Outcome in Renal Transplant Recipient: National Prospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 266 (actual)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This observational study is designed to analyse the urinary mRNA expression of Foxp3 and Vimentin, two genes involved in tolerance and early graft dysfunction in 500 renal transplant recipients from 17 renal transplant site in France and to determine the predictive value of these gene expression on the one year graft outcome including graft function, one-year graft histological analysis and incidence of acute rejection.

Detailed description

This observational study is designed to analyse the urinary mRNA expression of Foxp3 and Vimentin, two genes involved in tolerance and early graft dysfunction in 500 renal transplant recipients from 17 renal transplant site in France and to determine the predictive value of these gene expression on the one year graft outcome including graft function,

Conditions

• Function of Renal Transplant

Interventions

Type	Name	Description
OTHER	Renal Transplant	urinary sample at month 3, 6 and 12

Timeline

• Start date: 2010-09-01
• Primary completion: 2014-12-01
• Completion: 2015-01-01
• First posted: 2011-09-29
• Last updated: 2015-10-20

Locations

1 site across 1 country: France