Clinical Trials Directory

Trials / Terminated

TerminatedNCT01440192

Safety of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults With Stage II or III Pulmonary Sarcoidosis

A Phase 1B, Multi-Center, Open-Label, Single Dose Study to Evaluate the Safety of Intravenous Infusion of Human Placental-Derived Cells (PDA001) for the Treatment of Adults With Stage II or III Pulmonary Sarcoidosis.Sarcoidosis

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
4 (actual)
Sponsor
Celularity Incorporated · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the study is to assess the safety and tolerability of a single dose of PDA001 (given twice) in subjects with Stage II or III Pulmonary Sarcoidosis (PS) who are refractory to one or more of the following treatments for PS: methotrexate,immunosuppressants or cytotoxic agents.

Conditions

Interventions

TypeNameDescription
BIOLOGICALPDA001 (cenplacel-L)1 unit PDA001 (approximately 200 x 106 cells) IV on Days 1 \& 8

Timeline

Start date
2011-09-01
Primary completion
2014-02-01
Completion
2014-02-01
First posted
2011-09-26
Last updated
2018-03-01

Locations

4 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01440192. Inclusion in this directory is not an endorsement.

Safety of Intravenous Infusion of Human Placenta-Derived Cells (PDA001) for the Treatment of Adults With Stage II or III (NCT01440192) · Clinical Trials Directory