NCT01437579

Efficacy of Botulinum Toxin Type A in Patients With Bladder Pain Syndrome/Intersticial Cystitis and Hunners' Lesions

Randomized Controlled Trial for Efficacy of Botulinum Toxin Type A in Treatment of Patients Suffering Bladder Pain Syndrome/Interstitial Cystitis With Hunners' Lesions

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Moscow State University of Medicine and Dentistry · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The etiology of bladder pain syndrome is unknown. Therefore the management is directed to pain relief, as bladder pain is believed to drive both voiding frequency and nocturia. Botulinum toxin A has been shown to decrease noxious input. Several studies showed efficacy of botox for treatment of painful bladder. The aim of this study is to evaluate the efficacy of Botulinum toxin in patients who are suffering bladder pain syndrome with Hunner lesions during cystoscopy.

Conditions

• Interstitial Cystitis

Interventions

Type	Name	Description
PROCEDURE	intratrigonal injection of botulinum toxin	Bladder intratrigonal injection of botulinum toxin during cystoscopy under general anesthesia
PROCEDURE	cystoscopy	cystoscopy under general anesthesia

Timeline

• Start date: 2011-06-01
• Primary completion: 2011-12-01
• Completion: 2012-06-01
• First posted: 2011-09-21
• Last updated: 2011-09-21

Locations

1 site across 1 country: Russia