NCT01435746

Transfusion Requirements After Orthotopic Liver Transplantation

A Randomized, Controlled Pilot Trial of Transfusion Requirements After Orthotopic Liver

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University Medical Center Goettingen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The objective of this trial is to evaluate different transfusion strategies in patients after liver transplantation. Patients in the experimental arm will be given red blood cell (RBC) transfusion according to a liberal strategy, i. e., transfusions should be given, when hemoglobin concentration falls below 10 g/dl, and hemoglobin concentration should be maintained between 10 and 12 g/dl. Patients in the control arm will be given red blood cell (RBC) transfusion according to a restrictive strategy, i. e., transfusions should be given, when hemoglobin concentration falls below 8 g/dl, and hemoglobin concentration should be maintained between 8 and 10 g/dl.

Conditions

• Anemia

Interventions

Type	Name	Description
BEHAVIORAL	Red blood cell transfusion	The intervention of this trial is the regime of red blood cell transfusion. The control group will receive red blood cell transfusions according to a conservative regime, whereas the experimental group will receive red blood cell transfusion according to a liberal transfusion regime.

Timeline

• Start date: 2011-11-01
• Primary completion: 2012-11-01
• Completion: 2013-11-01
• First posted: 2011-09-19
• Last updated: 2022-08-08

Locations

1 site across 1 country: Germany