Trials / Completed
CompletedNCT01433237
Studying Biomarkers in Samples From Patients With Rhabdomyosarcoma
A Retrospective Study on the Diagnostic Value of Serum miR-206 in Rhabdomyosarcoma
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- Children's Oncology Group · Network
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research trial studies biomarkers in samples from patients with rhabdomyosarcoma.
Detailed description
OBJECTIVES: * Determine whether circulating muscle-specific microRNAs, especially serum miR-206, are potential biomarkers for rhabdomyosarcoma (RMS). OUTLINE: Archived serum samples are analyzed for miR-206 expression. PROJECTED ACCRUAL: A total of 15 samples from patients with alveolar rhabdomyosarcoma (RMS), 15 from patients with embryonal RMS, and 10 from patients without RMS will be accrued for this study.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | RNA analysis | |
| GENETIC | gene expression analysis | |
| OTHER | laboratory biomarker analysis |
Timeline
- Start date
- 2011-09-01
- Primary completion
- 2016-05-01
- Completion
- 2016-05-01
- First posted
- 2011-09-13
- Last updated
- 2016-05-19
Source: ClinicalTrials.gov record NCT01433237. Inclusion in this directory is not an endorsement.