Trials / Completed
CompletedNCT01430663
Diagnosing Pulmonary Aspergillosis in Patients With Hematological Malignancies: A Multicentre Prospective Evaluation of an Aspergillus PCR Assay and a Galactomannan ELISA in Bronchoalveolar Lavage Samples
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 87 (actual)
- Sponsor
- Heidelberg University · Academic / Other
- Sex
- All
- Age
- 5 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Diagnosing invasive pulmonary aspergillosis (IPA) remains a challenge in patients (pts) with hematological malignancies. The clinical significance of testing bronchoalveolar lavage (BAL) samples both with polymerase chain reaction (PCR) and Aspergillus galactomannan (GM) ELISA is unclear, and the BAL cutoff for GM has not been clearly defined yet. Using a validated nested PCR assay and a GM ELISA, we prospectively examine BAL samples from hematological patients at high risk of PA.
Conditions
Timeline
- Start date
- 2007-04-01
- Primary completion
- 2011-02-01
- Completion
- 2011-02-01
- First posted
- 2011-09-08
- Last updated
- 2020-04-20
Locations
9 sites across 2 countries: Austria, Germany
Source: ClinicalTrials.gov record NCT01430663. Inclusion in this directory is not an endorsement.