Trials / Completed
CompletedNCT01429948
Identification the Cause of Silent Cerebral infarctiON in Healthy Subjects (ICONS)
Novel Biomarkers for Personalized Therapy in Korean Patients With Ischemic Stroke
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 581 (actual)
- Sponsor
- Samsung Medical Center · Academic / Other
- Sex
- All
- Age
- 20 Years
- Healthy volunteers
- Not accepted
Summary
We hypothesized that paradoxical embolism may be one of the main mechanisms of silent cerebral infarction (SCI) located outside the perforating artery territory. In the present study, we evaluated the association between SCI and paradoxical embolism detected by agitated saline transcranial Doppler (TCD) monitoring in healthy subjects without history of stroke or transient ischemic attack (TIA). We also compared the frequency and amount of paradoxical embolism between healthy subjects with SCI and acute stroke patients with presumed cryptogenic embolism or conventional stroke mechanisms.
Conditions
Timeline
- Start date
- 2008-04-01
- Primary completion
- 2011-01-01
- Completion
- 2011-05-01
- First posted
- 2011-09-07
- Last updated
- 2011-09-07
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01429948. Inclusion in this directory is not an endorsement.