NCT01429701

Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol in Acute and Sub-acute Dermatitis Eczematous

Unicentric Comparing Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol to Betamethasone + Gentamicin + Tolnaftate + Clioquinol in Acute and Sub-acute Dermatitis Eczematous

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: EMS · Industry
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Dermatitis eczematous is a recurrent pruritic skin disorder which has a significant morbidity and impaired quality of life due specially pruritus and physical visible skin lesions. The purpose of this trial is evaluate the effectiveness of two different topic associations of drugs.

Detailed description

Study design: * Experiment duration: 22 days * 2 visits (days 0,7,15 and 22) * Reducing eczema area and severity index evaluation * Adverse events evaluation * Double blinded, non-inferiority, prospective parallel-group, intend to treat trial.

Conditions

• Eczema

Interventions

Type	Name	Description
DRUG	polymyxin B sulphate + prednisolone + benzocaine + clioquinol	applied 3 times / day at lesion
DRUG	betamethasone + gentamicin + tolnaftato + cleoquinol	applied 3 times / day at lesion

Timeline

• Start date: 2012-05-01
• Primary completion: 2012-06-01
• Completion: 2012-08-01
• First posted: 2011-09-07
• Last updated: 2021-02-24