NCT01428609

Blood Mercury Levels Following Retrograde Amalgam Surgeries

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Masoud Saatchi · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to determine the blood's mercury level of patients who had amalgam root end filling surgeries. It is to be examined if the mercury concentration in blood is elevated by using amalgam retroseal.

Detailed description

* A total of 14 patients who needs surgical root canal therapy (SRCT) participated in this clinical study. * The Isfahan University Human Subjects Review Committee approved the protocol of the study. * All patients filled in the consent form. * Apicoectomy with retrograde amalgam filling performed for all participant. * Blood samples were collected in three period of time immediately before and immediately after each surgery and also one week later. * Each time 10 ml blood was drawn from each patient. * Analysis of total mercury in blood samples was performed using cold-vapor atomic absorption spectrometry

Conditions

• Blood Mercury Concentration

Interventions

Type	Name	Description
PROCEDURE	Amalgam	In all surgical intervention a zinc free amalgam (Tytin. Kerr Sybron Crop., Romulus, MI) was used in the root end prepared spaces as root end filling material. Blood samples were collected in three period of time immediately before and immediately after each surgery and also one week later.

Timeline

• Start date: 2009-09-01
• Primary completion: 2009-12-01
• Completion: 2010-12-01
• First posted: 2011-09-05
• Last updated: 2012-03-22

Locations

1 site across 1 country: Iran