NCT01428323

Study of the Aerosol Deposition With Vented and Unvented Jet Nebulizer in Healthy Subjets

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 7 (estimated)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: Male
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Open-vent jet nebulizers are frequently used to promote drug lung deposition but their clinical efficacy and indications are not clear. Our study aimed to compare inhaled mass, and lung deposition of amikacin by using a jet nebulizer (Sidestream) under two different configurations: vented and unvented coupled to a 110 ml corrugated piece of tubing.

Conditions

• Aerosol Drug Therapy

Interventions

Type	Name	Description
DEVICE	Vented and Unvented Jet Nebulizer	Nebulizers used with 500mg aminoglycosides in 4ml until One minute after the sputerring point.

Timeline

• Start date: 2011-01-01
• Primary completion: 2011-09-01
• Completion: 2011-09-01
• First posted: 2011-09-02
• Last updated: 2011-09-02

Locations

1 site across 1 country: Belgium