NCT01427153

A Comparison of Manual Physical Therapy and Corticosteroid Injections for Knee Osteoarthritis

Orthopaedic Manual Physical Therapy Versus Corticosteroid Injections for Osteoarthritis of the Knee

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 156 (actual)
• Sponsor: Madigan Army Medical Center · Federal
• Sex: All
• Age: 38 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare an orthopaedic manual physical therapy (OMPT) approach to a corticosteroid injection approach for the management of knee osteoarthritis.

Detailed description

The purpose of this study is to compare a commonly offered clinical approach of a series of intra-articular steroid injections to an orthopaedic manual physical therapy (OMPT) approach consisting of manually applied passive movement and reinforcing exercise for the treatment of osteoarthritis of the knee (knee OA). A second purpose is to validate a clinical prediction rule (CPR) for patients unlikely to respond to the orthopaedic manual physical therapy approach in a pre-planned secondary analysis of data from the randomized clinical trial. Aim 1: To see if there is a significant difference in pain and function lasting out to 1 year for patients that receive a clinical approach consisting of a series of intra-articular steroid injections compared to those that receive a clinical approach consisting of orthopaedic manual physical therapy. Aim 2: To validate a clinical prediction rule of characteristics identified in a previous preliminary study that predicted which patients with knee OA would be unlikely to respond to OMPT.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
PROCEDURE	Orthopaedic manual physical therapy	OMPT consists of joint and soft-tissue mobilizations and the exercises that reinforce the manual techniques.
PROCEDURE	Corticosteroid Injection	Corticosteroid injection to the tibiofemoral joint

Timeline

• Start date: 2012-08-01
• Primary completion: 2018-05-01
• Completion: 2019-05-01
• First posted: 2011-09-01
• Last updated: 2025-01-27

Locations

2 sites across 1 country: United States