NCT01424007

Metabolism, Exercise and Nutrition at UCSD (MENU Study)

Diet Composition and Genetics: Effects on Weight, Inflammation and Biomarkers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 245 (actual)
• Sponsor: University of California, San Diego · Academic / Other
• Sex: Female
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

The purpose of the MENU Study is to examine whether there is a differential weight loss response to different dietary macronutrient composition (higher carbohydrate and lower fat versus lower carbohydrate and higher monounsaturated fat \[MUFA\] or lower carbohydrate and walnut-rich higher fat diets) in a weight loss intervention in healthy obese women, depending on insulin resistance status. Blood samples will be collected to enable analysis of potential mechanisms and differential response across subgroups.

Conditions

• Obese
• Nondiabetic

Interventions

Type	Name	Description
BEHAVIORAL	Weight loss	Participants would receive print materials on diet and exercise and attend group sessions that would meet weekly for the first 4 months, then every two weeks for the next 2 months, and then monthly for the next 6 months over the course of one year.

Timeline

• Start date: 2011-12-01
• Primary completion: 2016-07-01
• Completion: 2016-09-01
• First posted: 2011-08-26
• Last updated: 2019-07-05

Locations

1 site across 1 country: United States