NCT01423487

Efficacy and Safety of Metformin in Preventing Patients With Risperidone From Weight Gain and Amenorrhea

Efficacy and Safety of Metformin in Preventing Patients With Risperidone From Weight Gain and Amenorrhea:a 24-week, Randomized, Placebo-controlled, Double-blind, Fixed-dose Study

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Central South University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Some previous studies has demonstrated that Metformin can improve the weight gain which caused by antipsychotics. An our study, which will be published, also found that Metformin can improve the amenorrhea for patients with antipsychotics, approximately 60% patients recovery period. So the present study was designed to investigate the efficacy and safety of Metformin in preventing patients with Risperidone from weight gain and amenorrhea.

Conditions

• Weight Gain
• Amenorrhea

Interventions

Type	Name	Description
DRUG	Metformin	0.5g bid 26 weeks
OTHER	Starch tablets	0.5g bid 26 weeks

Timeline

• Start date: 2011-08-01
• Primary completion: 2013-02-01
• Completion: 2013-08-01
• First posted: 2011-08-26
• Last updated: 2012-08-02

Locations

1 site across 1 country: China