Trials / Unknown
UnknownNCT01421901
Antibiotics Versus Surgery in Acute Appendicitis
Antibiotics vs.Surgery in Acute Appendicitis;an Intention to Treat Prospective Randomised Study. The ASAA-study
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 218 (estimated)
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
The acute appendicitis (AA) is a very common disease with a life time risk 7-8% and the highest incidence in the second decades . The aetiology of AA is still poor understood: the commonest hypothesis refers to appendix obstruction followed by impairment of wall appendix barrier and thus wall perforation and/or abscess formation1. However some studies suggest that no-complicate and complicate appendicitis are different entities allowing a different treatment. The study aims to test the no inferiority in terms of efficacy of antibiotic treatment compared to surgery in a population with high probability to suffer of 1st episode of AA.The study aims to test the no inferiority in terms of efficacy of antibiotic treatment compared to surgery in a population with high probability to suffer of 1st episode of AA.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ertapenem | Ertapenem i.v,m 1g, once a day, 3 days |
| PROCEDURE | appendectomy |
Timeline
- Start date
- 2011-08-01
- Primary completion
- 2014-12-01
- Completion
- 2015-06-01
- First posted
- 2011-08-23
- Last updated
- 2014-06-17
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT01421901. Inclusion in this directory is not an endorsement.