NCT01419730

Vitamin D and Physical Activity on Bone Health

The Effect of High-Dose Vitamin D and Physical Activity on Bone Health in Breast Cancer Patients Receiving Hormonal Therapy

• Status: Active Not Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 191 (actual)
• Sponsor: University of Rochester · Academic / Other
• Sex: Female
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

This research will examine the effectiveness of vitamin D or placebo (the placebo is a tablet that looks like Vitamin D study drug, but has no Vitamin D study drug in it), with and without physical activity (walking and progressive resistance exercise), in treating bone loss in women who have undergone treatment for breast cancer. The investigators would also like to find out if the physical activity program improves cardiovascular fitness, energy expenditure, muscular strength, muscle mass, and balance. One hundred five (105) subjects are expected to take part in this study. The investigators don't know if bone loss in breast cancer survivors should be treated differently than bone loss in other women.

Conditions

• Bone Metabolism Biomarkers
• Bone Mineral Density
• Physical Fitness

Interventions

Type	Name	Description
DRUG	Vitamin D3	Vitamin D3 50,000 IU
BEHAVIORAL	Physical Activity	Progressive walking and resistance band exercise prescription for a period of 24 weeks

Timeline

• Start date: 2011-08-01
• Primary completion: 2024-12-30
• Completion: 2026-12-30
• First posted: 2011-08-18
• Last updated: 2026-04-07

Locations

1 site across 1 country: United States