Trials / Terminated
TerminatedNCT01419002
Study to Evaluate if Neoadjuvant Radiotherapy Improves Recurrence Free Survival in Pancreatic Head Cancer
Neoadjuvant Radiotherapy in Patients With Primary Resectable Adenocarcinoma of the Pancreatic Head Plus Adjuvant Chemotherapy: a Randomized Controlled Phase III Trial
- Status
- Terminated
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 5 (actual)
- Sponsor
- CHIR-Net · Network
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Net-Pac investigates if radiation prior to surgical resection improves survival in patients with pancreatic head cancer without metastases.
Detailed description
The trial is designed to show that neoadjuvant radiotherapy followed by surgery improves local recurrence free survival compared to surgery alone in patients with resectable adenocarcinoma of the pancreatic head.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | neoadjuvant RTx | Neoadjuvant radiotherapy with external intensity modulated beam radiation followed by duodenopancreatectomy and adjuvant chemotherapy according to German S3 guidelines. |
| PROCEDURE | Surgery | Surgery and adjuvant chemotherapy according to German S3-guidelines |
Timeline
- Start date
- 2011-10-01
- Primary completion
- 2014-10-01
- Completion
- 2014-10-01
- First posted
- 2011-08-17
- Last updated
- 2015-07-29
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT01419002. Inclusion in this directory is not an endorsement.