NCT01418027

Combined Intensive and Conventional Exercise on Nonalcoholic Fatty Liver Disease (NAFLD)

Combined Intensive and Conventional Exercise Intervention of Nonalcoholic Fatty Liver Disease

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 220 (actual)
• Sponsor: Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The prevalence of NAFLD is 50-70% in obese people. A decrease of calorie intake and increase of physical activity are recommended as an effective approach for the prevention and treatment of NAFLD. However, the exercise model for NAFLD intervention is understudied. In the present study we aim to compare the effect of intensive and conventional exercise interventions on NAFLD.

Conditions

• Non-alcoholic Fatty Liver Disease (NAFLD)

Interventions

Type	Name	Description
OTHER	Intensive exercise	Subjects conduct an aerobic exercise at 65-80% maximum oxygen consumption for 30 minutes each day, five days a week, totally for 6 months.Subsequently, moderate physical activity(3.0-6.0 MET s) at 150 min/wk for 6 months.
OTHER	Conventional exercise	Subjects receive moderate physical activity(3.0-6.0 MET s) at 150 min/wk(30 min per day, five days a week) for 12 months.

Timeline

• Start date: 2011-08-01
• Primary completion: 2013-12-01
• Completion: 2013-12-01
• First posted: 2011-08-16
• Last updated: 2014-09-01

Locations

1 site across 1 country: China