NCT01417715

Endomicroscopy for Assessment of Mucosal Healing

Advanced Endoscopic Imaging Using Endomicroscopy for Assessment of Mucosal Healing in IBD

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 84 (actual)
• Sponsor: University of Erlangen-Nürnberg Medical School · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Inflammatory bowel disease (IBD) encompasses two major forms of chronic intestinal disorders, Crohn's disease and ulcerative colitis (UC). Diagnosis is based on several macroscopic and histologic features including patterns of inflammation, crypt abscesses and granulomas. Confocal laser endomicroscopy (CLE) is rapidly emerging as a valuable tool for gastrointestinal endoscopic imaging, enabling the endoscopist to obtain an "optical biopsy" of the gastrointestinal mucosa during the endoscopic procedure. The main objective of this study is to determine endomicroscopic features of mucosal healing in patients with IBD.

Conditions

• Crohn´s Disease
• Ulcerative Colitis

Interventions

Type	Name	Description
DEVICE	Endomicroscopy	Patients will undergo advanced endoscopic imaging using endomicroscopy. Findings will be compared to histopathological and clinical results.

Timeline

• Start date: 2011-08-01
• Primary completion: 2014-05-01
• Completion: 2014-08-01
• First posted: 2011-08-16
• Last updated: 2020-12-14

Locations

1 site across 1 country: Germany