NCT01417702

Endoscopy for Assessment of Mucosal Healing in IBD

Advanced Endoscopic Imaging Using HD+ Endoscopy and i-Scan for Assessment of Mucosal Healing in IBD

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 232 (actual)
• Sponsor: University of Erlangen-Nürnberg Medical School · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Inflammatory bowel disease (IBD) encompasses two major forms of chronic intestinal disorders, Crohn's disease and ulcerative colitis (UC). Diagnosis is based on several macroscopic and histologic features including patterns of inflammation, crypt abscesses and granulomas. i-Scan use an endoscopic image from the video processor and reconstruct virtual images in real time, resulting in an improved contrast of the capillary patterns and enhancement of the mucosal surface (so called virtual chromoendoscopy). The main objective of this study is to determine endoscopic features of mucosal healing in patients with IBD and to compare these features to clinical and histological data in order to establish a new endoscopic classification of mucosal healing and to evaluate mucosal healing as a parameter of remission and relapse.

Conditions

• Crohn´s Disease
• Ulcerative Colitis

Interventions

Type	Name	Description
DEVICE	High-definition white light endoscopy and i-Scan	Patients will undergo advanced endoscopic imaging. Findings will be compared to histopathological and clinical results.

Timeline

• Start date: 2011-08-01
• Primary completion: 2014-05-01
• Completion: 2014-11-01
• First posted: 2011-08-16
• Last updated: 2020-12-14

Locations

1 site across 1 country: Germany