NCT01416818

Treatment of Depression in Parkinson's Disease

A Randomized, Double-Blind, Placebo-Controlled Study of "Xiaoyao Pill" Treatment of Depression in Patients With Parkinson's Disease

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Xuanwu Hospital, Beijing · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The goal of this study is to evaluate the efficacy of Traditional Chinese Medicine-"Xiaoyao Pill" (Herb extracts)on depression, compared to placebo and "Bupleurum+Ginkgo" in patients with Parkinson's disease.

Detailed description

Depression as the most common non-motor comorbidity of Parkinson's disease (PD), have a negative impact on disability and quality of life. Traditional Chinese Medicine has shown effects on several depression. It is not known if TCM also is effective for depression in PD. This study is to investigate "Xiaoyao Pill", an antidepressant in TCM, on depression in PD. A total of 60 patients with depression in PD will be randomized to each of the three arms.

Conditions

• Depression in Parkinson's Disease

Interventions

Type	Name	Description
DRUG	Xiaoyao Pill	herb extracts,were received two times a day for 12 weeks without dose changing.
DRUG	Bupleurum+Ginkgo	herb extracts, were received two times a day for 12 weeks without dose changing.
DRUG	placebo	The placebo looked like herb extracts and were also received two times a day for 12 weeks without dose changing.

Timeline

• Start date: 2008-05-01
• Primary completion: 2011-10-01
• Completion: 2011-12-01
• First posted: 2011-08-15
• Last updated: 2011-08-15

Locations

1 site across 1 country: China