NCT01414894

Intensive Management of Pressure and Volume Expansion in Patients With Subarachnoid Hemorrhage

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of our study is to determine how well Triple-H works and how safe it is. The investigators are hoping to determine the effects of starting the therapy early and to explore if hypervolemia and/or hypertension are beneficial, and what the optimal target ranges are.

Detailed description

Efficacy of Triple-H therapy.

Conditions

• Subarachnoid Hemorrhage

Interventions

Type	Name	Description
OTHER	Fluid manipulation	Patients are treated with conventional fluid replacement (Normovolemia) or increased the fluid replacement (Hypervolemia) for 10 days.
OTHER	Blood Pressure Manipulation	Patients are treated with maintenance of blood pressure in a normal range (Conventional Blood Pressure) or increased the blood pressure (Augmented Blood Pressure) for 10 days.

Timeline

• Start date: 2010-04-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2011-08-11
• Last updated: 2013-06-20