NCT01414673

HCG Versus Spontaneous LH in Intrauterine Insemination (IUI ) Cycles

Spontaneous Triggering of Ovulation vs. Administration of Human Chorionic Gonadotropin in Patients Undergoing Intrauterine Insemination: a Prospective Randomized Study.

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 300 (actual)
• Sponsor: Universitair Ziekenhuis Brussel · Academic / Other
• Sex: Female
• Age: 18 Years – 36 Years
• Healthy volunteers: Accepted

Summary

We recently reported the superiority of the natural cycle to a natural cycle controlled by the administration of human chorionic gonadotropin (hCG) for planning the frozen-thawed embryo transfer cycles, demonstrating a probable negative impact of exogenous hCG on endometrial receptivity.Based on the above findings we conducted the first prospective study that assesses whether there is a difference in pregnancy rate after intrauterine insemination (IUI) in a natural cycle with spontaneous luteinizing hormone (LH) rise compared to natural cycles controlled by hCG for final ovulation.

Conditions

• Spontaneous Triggering of Ovulation vs. Administration of Human Chorionic Gonadotropin in Patients Undergoing IUI

Interventions

Type	Name	Description
DRUG	HCG	5000 IU

Timeline

• Start date: 2009-04-01
• Primary completion: 2011-07-01
• Completion: 2011-08-01
• First posted: 2011-08-11
• Last updated: 2011-08-11

Locations

1 site across 1 country: Belgium