NCT01411748

Comparison of Saccharomyces Boulardii and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 140 (estimated)
• Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital · Academic / Other
• Sex: All
• Age: 1 Day – 90 Days
• Healthy volunteers: Not accepted

Summary

Probiotics are favorable microorganisms that regulate the flora of the gastrointestinal system and stimulate the immune system. Saccharomyces boulardii was shown to reduce candida colonization. The objective of this study is to evaluate the efficacy of prophylactic S boulardii in reducing the candida colonization and infection in very low birth weight infants.

Conditions

• Anticandidal Property of Saccharomyces Boulardii on Very Low Birth Weight Infants

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Reflor	5 million unit/day, orally, beginning on the second day of life, until discharge from hospital
DRUG	mikostatin	50000 unit/3 times a day, both for orally and by orogastric route

Timeline

• Start date: 2011-07-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2011-08-08
• Last updated: 2011-08-08

Locations

1 site across 1 country: Turkey (Türkiye)