NCT01410682

Oral Care and Gram-negative Pathogen in Children

Oral Care and Oropharyngeal and Tracheal Colonization by Gram-negative Pathogens in Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (actual)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: All
• Age: 29 Days – 18 Years
• Healthy volunteers: Not accepted

Summary

Critical care nursing interventions related to oral care can reduce the microorganisms in the oropharynx available for translocation to other sites. THis is a randomized, controlled and double blinded study performed in a pediatric intensive care unit (PICU) from a Brazilian university hospital which objectives were to analyze 0.12% chlorhexidine digluconate influence on Gram-negative pathogens colonization of oropharyngeal and tracheal secretions of mechanically ventilated children.

Conditions

• Tracheal and Oropharyngeal Colonization by Gram-negative Pathogens

Interventions

Type	Name	Description
OTHER	0,12% digluconate chlorhexidine	Oral care with 0.12% Chlorhexidine Digluconate and toothbrushing is realized twice a day and took about 10 minutes to complete, depending on the child's acceptance and clinical conditions.
OTHER	toothbrushing	Gel is applied on a toothbrush, and the teeth are cleaned in quadrants; all teeth surfaces are cleaned (vestibular, lingual, occlusal, and incisal). After each quadrant is cleaned, 10 mL of water (dispensed via a syringe) is used to rinse the quadrant and continual aspiration is used to remove all the gel and debris. After all the teeth are cleaned, the ventral surface of the tongue is brushed with posterior to anterior movements.

Timeline

• Start date: 2005-06-01
• Primary completion: 2007-06-01
• Completion: 2007-06-01
• First posted: 2011-08-05
• Last updated: 2011-08-05