NCT01409551

Video-assisted Hyperthermic Pleural Chemoperfusion vs Talc Pleurodesis for Refractory Malignant Pleural Effusions.

Video-assisted Hyperthermic Pleural Chemoperfusion Versus Bed-side Talc Slurry Pleurodesis for Refractory Malignant Pleural Effusions.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Theagenio Cancer Hospital · Other Government
• Sex: All
• Age: 75 Years
• Healthy volunteers: Not accepted

Summary

Aim of this study is to compare two methods of pleurodesis for refractory malignant pleural effusions, in terms of safety and efficacy.

Detailed description

The study compares prospectively two groups of patients with refractory maignant pleural effusion. Group A consists of patients undergoing video-assisted hyperthermic pleural chemoperfusion (with a pump machine) and group B includes patients undergoing bed-side tube thoracostomy and talc slurry pleurodesis.

Conditions

• Safety of Intervention
• Efficacy of Intervention
• Cost Effectiveness

Interventions

Type	Name	Description
PROCEDURE	VATS hyperthermic chemoperfusion	VATS, adhesiolysis, hyperthermic chemoperfusion (with a pump machine)
PROCEDURE	Bedside talc slurry pleurodesis	Bedside tube thoracostomy under local anesthesia. Bedside talc slurry pleurodesis.

Timeline

• Start date: 2011-08-01
• Primary completion: 2014-11-01
• Completion: 2014-11-01
• First posted: 2011-08-04
• Last updated: 2014-11-17

Locations

1 site across 1 country: Greece