Trials / Completed
CompletedNCT01407731
Protein Expression in Human Neuroblastoma Tumor Samples
Analysis of Intersectin Expression in Primary Human Neuroblastomas
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- Children's Oncology Group · Network
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Studying protein expression in samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat neuroblastoma. PURPOSE: This laboratory studying is looking at protein expression in tumor tissue samples from patients with neuroblastoma.
Detailed description
OBJECTIVES: * To determine whether intersectin (ITSN1) proteins are present at elevated levels in primary human tumor samples. OUTLINE: Archived tumor tissue samples are analyzed for intersectin (ITSN1) expression by western blot assays with enhanced chemiluminescence and exposed to X-ray film. The films are scanned, and levels of ITSN1 signal are quantified by densitometry.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | protein expression analysis | |
| GENETIC | western blotting | |
| OTHER | laboratory biomarker analysis |
Timeline
- Start date
- 2011-07-01
- Primary completion
- 2016-05-01
- Completion
- 2016-05-01
- First posted
- 2011-08-02
- Last updated
- 2016-05-17
Source: ClinicalTrials.gov record NCT01407731. Inclusion in this directory is not an endorsement.