NCT01406860

Droperidol Versus Metoclopramide + Diphenhydramine for the Treatment of Primary Headaches

Droperidol Versus Metoclopramide + Diphenhydramine for the Treatment of Primary Headaches in the Emergency Department: A Prospective Randomized, Double-blinded Trial.

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: University of Iowa · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if droperidol is equally as effective as metoclopramide for treatment of primary headaches in the Emergency Department.

Conditions

• Primary Headaches (Includes Migraines, Tension, Cluster Headaches)

Interventions

Type	Name	Description
DRUG	Droperidol	Droperidol 1.25 mg IV x 1, may repeat 0.625 mg if needed at 60 minutes
DRUG	Metoclopramide + diphenhydramine	Metoclopramide 20 mg IV infusion q30 minutes as needed with a maximum of 4 doses + Diphenhydramine 25 mg IV injection x 1 given with the first dose of metoclopramide IV infusion and repeated x 1 given with the third metoclopramide IV infusion.

Timeline

• Start date: 2011-07-01
• Primary completion: 2012-07-01
• Completion: 2012-07-01
• First posted: 2011-08-01
• Last updated: 2017-12-05
• Results posted: 2017-12-05

Locations

1 site across 1 country: United States