NCT01406496

Best Timing of Insulin Bolus Before Meals of Different Contents

The Effect of Food Content and Optimal Timing of Pre-meal Insulin Bolus on the Postprandial Glycemic Control in Children With Type 1 Diabetes

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: Kaplan Medical Center · Academic / Other
• Sex: All
• Age: 8 Years – 30 Years
• Healthy volunteers: Accepted

Summary

Post-meal glucose excursions may contribute to the development of diabetes-related complications. These glucose excursions are affected by the food content of the meal and the timing of insulin injection (or insulin pump-bolus) before meal. The best timing for insulin bolus (by pump) is controversial. The aim of the study is to examine three different timings of insulin bolus in three types of breakfast meals that contain carbohydrates, carbohydrates + proteins and carbohydrate+ fat. The 3h post-meal glucose excursions will be recorded by continuous glucose monitoring system. The results obtained in the diabetic patients will be compared to those obtained in a group of healthy individuals that will consume similar meals.

Conditions

• Type 1 Diabetes Mellitus

Interventions

Type	Name	Description
DRUG	insulin	Three different timings of insulin delivered by a pump

Timeline

• Start date: 2011-08-01
• Primary completion: 2013-10-01
• Completion: 2013-12-01
• First posted: 2011-08-01
• Last updated: 2013-02-22

Locations

1 site across 1 country: Israel