Trials / Unknown
UnknownNCT01406041
Disturbance of Water and Sodium Metabolism After Surgery of Sellar Lesions, and Correspond Clinical Strategy
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 350 (estimated)
- Sponsor
- Southern Medical University, China · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The fluid and electrolyte imbalance (FEI) is pretty common encountered during the clinical process of patients suffered sellar lesions. Moreover, if the patients are undergone the surgery for remove the lesion, FEI happens in all cases without exception. Hypo- and hyper-natremia is the most common electrolyte disorder, which is directly correlated to the patients' outcome. However, in clinical works, different sellar diseases cause variant features of FEI. For example, after the surgery of craniopharyngioma, the hyponatremia and hypernatremia always happen alternatively even without any precursor manifestation. Under this situation, it is quite difficult for fluid supplement. In contrast, the severe FEI will cause poor outcome, even death. So it is necessary to systematically collect and review the clinical data of sellar lesions. Through the analysis of variant FEI patterns of sellar diseases, more precise strategy for clinical fluid replacement will be proposed.
Conditions
- The Patients Suffered With Sellar Diseases
- The Fluid and Electrolyte Imbalance Happened After Surgery
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Chemical and physical detection | CVP, Urine volume per day, Blood electrolytes, Urine sodium per day, Pituitrin |
Timeline
- Start date
- 2011-02-01
- Primary completion
- 2020-01-30
- Completion
- 2021-05-12
- First posted
- 2011-07-29
- Last updated
- 2020-03-19
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT01406041. Inclusion in this directory is not an endorsement.