NCT01400009

Vitamin D Replacement in Statin-Induced Myopathy

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Pretreating people with replacement doses of vitamin D will allow them to tolerate Statin medications that have caused muscle pain for them in the past.

Detailed description

Patients who have been unable to tolerate statin medications due to muscle pain will be randomly assigned to receive vitamin D or placebo for 6 weeks before reintroducing their statin medication. The investigators will judge whether vitamin D in the manner administered in the study reduces the myalgia with statins and allows patients to remain on these important medications.

Conditions

• HMG COA Reductase Inhibitor Adverse Reaction

Interventions

Type	Name	Description
DRUG	Vitamin D (Cholecalciferol )	10,000 IU tablets. 50,000 initial dose, followed by weekly doses of 10,000 IU
DRUG	Placebo	Standard Placebo made of Lactose 100 mg

Timeline

• Start date: 2010-10-01
• Primary completion: 2012-07-01
• Completion: 2012-07-01
• First posted: 2011-07-22
• Last updated: 2015-04-07

Locations

1 site across 1 country: Canada