NCT01399203

Contrast Medium Volume and Contrast-induced Nephropathy After Percutaneous Coronary Intervention

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 2,000 (estimated)
• Sponsor: Guangdong Provincial People's Hospital · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

To investigate the predictive value of the contrast media volume to creatinine clearance (V/CrCl) ratio for the risk of contrast-induced nephropathy (CIN) (i.e., within 48-72 h) and to determine a relatively safe V/CrCl cut-off value to avoid CIN in patients following PCI

Detailed description

contrast media volume to creatinine clearance (V/CrCl) ratios were obtained from consecutive consenting patients after unselective PCI. Receiver-operator characteristic (ROC) curves were used to identify the optimal sensitivity for the observed range of V/CrCl. The predictive value of V/CrCl for the risk of CIN was assessed using multivariate logistic regression.

Conditions

• Contrast Induced Nephropathy

Timeline

• Start date: 2010-01-01
• Primary completion: 2011-10-01
• Completion: 2012-01-01
• First posted: 2011-07-21
• Last updated: 2011-08-03

Locations

1 site across 1 country: China